Nucleus — controls the cell; holds the genetic instructions (DNA).
Cytoplasm — jelly where the cell's reactions happen.
Cell membrane — controls what goes in and out.
Mitochondria — release energy by respiration.
Cell wall (plants) — made of cellulose, gives support and shape.
Vacuole (plants) — holds cell sap and keeps the cell firm.
Chloroplasts (plants) — contain chlorophyll for photosynthesis. Only cells in green parts have them; root cells do not.
Common mistake: people say plant cells "don't have" the parts animal cells have. Not true — plant cells have everything an animal cell has, plus three extras (wall, vacuole, chloroplasts).
Quick check
Which parts are plant-only?
?A student looks at a cell under a microscope and sees a cell wall, chloroplasts and a large permanent vacuole. What kind of cell is it?
Cells and organisation
Specialised cells
In a multicellular body, cells become specialised — their structure is adapted to a particular job:
Red blood cell — no nucleus, so it can pack in more haemoglobin and carry more oxygen. Its dimpled disc shape gives a big surface area for oxygen to move in and out.
Nerve cell (neurone) — very long and thin to carry electrical signals over distances.
Sperm cell — has a tail to swim to the egg.
Root hair cell — a long "hair" that gives a big surface area to absorb water.
Each cell's shape fits its job. (Not to scale.)
Structure fits function again: each cell's shape is a clue to the job it does.
Match it
Cell part ↔ its job
Tap a cell part on the left, then tap the job it does on the right.
Cell part
Its job
Cells and organisation
From cells to a whole organism
In a multicellular organism, cells are organised in levels, from small to big:
A tissue is a group of similar cells that do the same job.
An organ is made of different tissues working together.
An organ system is a group of organs working together.
Cells → tissues → organs → organ systems → the whole organism.
Common mistake: mixing up the order. From smallest to biggest: cell → tissue → organ → organ system → organism.
Cells and organisation
Diffusion: in and out of cells
Oxygen and carbon dioxide cross the cell membrane by diffusion.
Diffusion is when particles spread from where there are lots of them (a high concentration) to where there are fewer (a low concentration). It happens by itself: the cell does not have to push.
Oxygen diffuses into the cell and carbon dioxide diffuses out: each moves from a high to a low concentration.
Oxygen diffuses out of red blood cells and into body cells, where respiration uses it up.
Carbon dioxide, made by respiration, diffuses out of body cells into the blood.
Common mistake: particles do not "choose" where to go. They move at random, and overall they spread from high to low concentration.
Quick check
Which way does oxygen go?
?A body cell uses up oxygen in respiration, so there is less oxygen inside it than in the blood outside. Which way does oxygen diffuse?
Mission 1 check
Why does a red blood cell have no nucleus?
?A red blood cell has no nucleus. How does this help it do its job?
Mission 2 of 5
How do you straighten your arm?
Make a guess: a muscle can only pull. So how do you straighten your arm?
Skeletal & muscular systems
What the skeleton does
Your skeleton is more than a frame. It has four main functions:
Support — holds the body up and gives it shape.
Protection — the skull guards the brain; the ribs guard the heart and lungs.
Movement — bones act as levers that muscles pull on.
Making blood cells — new blood cells are made inside bone marrow.
Bones meet at joints (like the knee and elbow). Joints let the skeleton bend.
Support, protection, movement and making blood cells. (Simplified, not to scale.)Skeletal & muscular systems
Muscles work in pairs
A muscle can only pull (contract) — it can't push. So muscles are arranged in antagonistic pairs that pull the bone in opposite directions.
To bend the arm: the biceps contracts while the triceps relaxes. To straighten it, they swap.
Watch out: when one muscle contracts to move the joint, its partner relaxes — that is what "antagonistic" means.
Mission 2 check
How do you straighten your arm?
?To straighten your arm at the elbow, what happens to the two muscles?
Mission 3 of 5
How does a sandwich reach your muscles?
Make a guess: how does a sandwich reach your muscles?
Nutrition and digestion
A balanced diet
A healthy diet contains the right amounts of seven things, each with a job:
Carbohydrates — the body's main energy source.
Lipids (fats & oils) — energy store and insulation.
Proteins — for growth and repair.
Vitamins and minerals — small amounts keep the body working (e.g. iron for blood).
Dietary fibre — keeps food moving through the gut.
Water — needed for nearly every process.
Imbalance has consequences: too much energy in the diet can lead to obesity; too little food causes starvation; missing a vitamin or mineral causes a deficiency disease.
Nutrition and digestion
How much energy do you need?
The energy in food is measured in kilojoules (kJ). A typical 12-year-old needs about 9,000 kJ a day. Older or more active people need more.
Food labels give the energy in 100 g (or 100 ml for drinks). For your portion:
energy = energy per 100 g × mass in g ÷ 100
Bread: 1,000 × 80 ÷ 100 = 800 kJ.
Add up each food to get a meal's energy. (Typical values, rounded.)
Common mistake: using the label value as it is. It is for 100 g, not for your portion.
Quick check
Energy in a portion
?Crisps have about 2,200 kJ per 100 g. How much energy is in a 50 g bag?
Nutrition and digestion
Testing food (the basics)
In the lab you can test which nutrients a food contains using colour-change tests:
Sugar (glucose) — add Benedict's and heat: blue turns brick-red / orange.
Protein — add Biuret solution: blue turns purple / lilac.
Lipid (fat) — the emulsion test: a cloudy white layer forms.
Tip: remember starch → iodine → blue-black. It's the one you'll be asked about most.
Quick check
Reading a food test
?A student adds iodine solution to a slice of potato and it turns blue-black. What does this show the potato contains?
Nutrition and digestion
The digestive system
Food is too big to enter your blood, so the digestive system breaks it down. Follow the journey:
Food travels: mouth → oesophagus → stomach → small intestine → large intestine.
The liver makes bile and the pancreas makes enzymes that help digestion happen in the small intestine. There, digested food is absorbed into the blood, which carries it to every cell in the body.
Nutrition and digestion
Enzymes and helpful bacteria
Enzymes are biological catalysts — they speed up the breakdown of big food molecules into small ones that can be absorbed. Different enzymes work on different foods (e.g. one for starch, one for protein).
An enzyme speeds up the breakdown of a big food molecule into small ones. (Not to scale.)
Your gut also contains huge numbers of helpful bacteria. They help digest food, make some vitamins, and crowd out harmful microbes.
Common misconception: enzymes are not alive. They are special protein molecules made by living cells — but the molecule itself is not a living thing and cannot "die". Very high temperatures or the wrong pH denature (change the shape of) an enzyme so it stops working.
Quick check
What is an enzyme?
?Which statement about digestive enzymes is correct?
Match it
Organ ↔ its function
Tap an organ on the left, then tap the job it does on the right.
Organ
Its function
Mission 3 check
How does a sandwich reach your muscles?
?A sandwich is far too big to get into your blood. How does it reach your muscles?
Mission 4 of 5
Where does your body release energy?
Make a guess: what releases the energy from your food?
Gas exchange systems
The breathing system
Your lungs take in the oxygen your cells need and get rid of carbon dioxide. Air travels down the trachea, branches into bronchi and bronchioles, and ends at tiny air sacs called alveoli.
Alveoli are adapted for gas exchange: a huge surface area, thin walls and a good blood supply.
Breathing in: the diaphragm and rib muscles contract, the chest gets bigger, pressure inside drops, and air rushes in. Breathing out is the reverse.
Gas exchange systems
A model of breathing: the bell jar
A model shows how breathing moves air. The jar is the chest, the balloons are the lungs, the tube is the trachea and bronchi, and the rubber sheet is the diaphragm.
Pull the sheet down and air rushes in; push it up and air is pushed out.
Pull the sheet down: the space inside the jar gets bigger, so the pressure drops. Air rushes in and the balloons inflate. Push it up: the space gets smaller, the pressure rises, and air is pushed out. Air always moves from higher to lower pressure.
Limits of the model: in a real chest, the ribs also move up and out. The jar's walls cannot move.
Quick check
Pulling the sheet
?In the bell-jar model, you pull the rubber sheet down. What happens to the balloons?
Gas exchange systems
Measuring lung volume
How much air can your lungs push out in one breath? You can measure it by displacing water.
Fill a bottle marked in litres with water. Stand it upside down in a trough of water.
Take a deep breath, then breathe out fully through the tube.
Your air pushes water out of the bottle. Read the volume of air on the scale.
The air you breathe out takes the place of the water. (Simplified, not to scale.)
Repeat three times and work out the mean.
Stay safe: use a clean mouthpiece. Only breathe out through the tube, never in.
Gas exchange systems
Breathing is not respiration
These two words are easy to mix up, but they mean different things:
Breathing — moving air in and out of the lungs (a physical action of muscles).
Respiration — the chemical reaction inside every cell that releases energy from glucose, using oxygen.
Common misconception: "breathing = respiration" is wrong. Breathing just supplies the oxygen that respiration uses inside the cells (in the mitochondria). Smoking damages the alveoli, and asthma narrows the airways — both make it harder to get oxygen into the blood.
Write it
Explain the difference
✎In one or two sentences, explain the difference between breathing and respiration.
Model answer
Breathing is moving air in and out of the lungs using muscles. Respiration is the chemical reaction inside cells that releases energy from glucose using the oxygen that breathing supplies.
Health
Diet, exercise, drugs and smoking
Your lifestyle choices affect how well your body systems work:
Balanced diet + exercise keep the heart, muscles and skeleton healthy and help control body mass.
Smoking damages the alveoli and reduces how much oxygen the blood can carry.
Recreational drugs and alcohol can change behaviour and damage organs; some are addictive.
During pregnancy, harmful substances can pass through the placenta (where food and oxygen pass from mother to baby) and harm the foetus.
Smoking damages the alveoli: less surface area, so less oxygen gets into the blood. (Simplified.)
Big picture: scientists study the links between diet, exercise, drugs and health to give advice — this is real, evidence-based science.
Write it
Smoking and the lungs
✎Give one way that smoking can affect the gas exchange system, and say why that is a problem for the body.
Model answer
Smoking damages the alveoli, reducing the surface area for gas exchange. This means less oxygen can pass into the blood, so the body's cells get less oxygen for respiration and the person becomes short of breath.
Mission 4 check
Where does your body release energy?
?Breathing brings oxygen into your body. What actually releases the energy from your food?
Gas exchange systems
Exercise and asthma
Exercise: your muscles need more oxygen, so you breathe faster and deeper. More carbon dioxide is removed too. With regular exercise you get fitter: the same activity leaves you less out of breath.
Asthma: a trigger, such as dust, pollen or smoke, makes the airways narrow. The muscle around them tightens, the lining swells and extra mucus is made.
An airway cut across. (Simplified, not to scale.)
With narrow airways, less air reaches the alveoli. The person may cough, wheeze and feel short of breath. A reliever inhaler relaxes the muscle and opens the airways.
Gas exchange systems
How leaves exchange gases
Plants exchange gases through tiny pores in their leaves called stomata (one is a stoma). Most are on the lower surface. Two guard cells around each stoma open and close it.
Gases diffuse in and out through an open stoma. (Not to scale.)
By day, in the light:
carbon dioxide diffuses in, for photosynthesis;
oxygen diffuses out;
water vapour escapes too.
Common mistake: thinking plants do not respire. They respire all the time. In bright light, photosynthesis uses carbon dioxide faster than respiration makes it, so overall carbon dioxide goes in.
Mission 5 of 5
How does pollen get from flower to flower?
Make a guess: how does pollen get from flower to flower?
Reproduction
Human reproduction
Humans reproduce sexually. Special sex cells called gametes join together:
The male gamete is the sperm (made in the testes).
The female gamete is the egg / ovum (made in the ovaries).
Fertilisation is when a sperm joins an egg. The fertilised egg grows into an embryo.
Two gametes join at fertilisation. (Not to scale: an egg is far bigger than a sperm.)
The menstrual cycle is a roughly monthly cycle in females: the lining of the uterus builds up ready for a fertilised egg. If none arrives, the lining breaks down (a period) and the cycle starts again.
Gestation is pregnancy — in humans it lasts about 9 months. The developing baby gets food and oxygen from the mother through the placenta, which is why the mother's lifestyle (e.g. smoking or alcohol) can affect the foetus.
Quick check
Gametes and fertilisation
?What is fertilisation?
Reproduction
The reproductive systems
Female: about once a month, an ovary releases an egg. It moves along an oviduct towards the uterus (womb).
Male: the testes make sperm. Sperm travel along the sperm ducts. Glands add a fluid, making semen, which leaves through the urethra in the penis.
Each system, seen from the front. (Simplified, not to scale.)
Sperm released into the vagina swim through the cervix and uterus to the oviducts. If a sperm meets an egg there, fertilisation can happen.
Reproduction
The menstrual cycle
From puberty, the menstrual cycle repeats about every 28 days. The length varies from person to person.
A typical 28-day cycle. Day 1 is the first day of a period.
The uterus lining builds up, ready for a fertilised egg.
About halfway through, an ovary releases an egg: ovulation.
If the egg is not fertilised, the lining breaks down and leaves through the vagina: a period. Then the cycle starts again.
Reproduction
Gestation, the placenta and birth
The embryo settles into the thick uterus lining and grows into a foetus. At the placenta, food and oxygen pass from the mother's blood to the foetus. Carbon dioxide and waste pass back.
Late in gestation, head down. (Simplified, not to scale.)
The mother's lifestyle affects the foetus:
Smoking: less oxygen reaches it, so it is more likely to be born early and small.
Alcohol can damage its developing brain.
Drugs: some cross the placenta; a baby can be born dependent on them.
Diet: a balanced diet gives it what it needs to grow.
Birth: after about 9 months, the uterus muscles contract, the cervix widens, and the baby is pushed out through the vagina.
Quick check
Smoking in pregnancy
?Why can smoking during pregnancy harm a foetus?
Reproduction
Plant reproduction and pollination
Flowers are the reproductive organs of a plant. Their key parts:
Stamen (anther + filament) — the male part; the anther makes pollen.
Carpel (stigma, style, ovary) — the female part; the ovary holds the ovules.
Inside a flower: the stamens are the male parts; the carpel is the female part. (Simplified.)
Pollination is the transfer of pollen from an anther to a stigma. It can be carried by insects (bright petals, nectar, sticky pollen) or by the wind (small dull flowers, lots of light pollen). After pollination, fertilisation forms seeds and fruits, which are then dispersed.
Why it matters: insect pollination of crops is vital for human food security — many of the foods we eat rely on pollinators like bees.
Reproduction
Seed dispersal
A plant can't move from place to place, so its seeds need help to get away from the parent plant. This is seed dispersal. Far away, a seedling does not compete with its parent for light and water.
Three ways seeds are spread. (Not to scale.)
Wind: light seeds with wings (sycamore) or parachutes (dandelion).
Animals: seeds in eaten fruits pass out in droppings; hooked fruits catch on fur.
Bursting pods: some pods dry out and split open, flinging the seeds out.
Investigate it: time how long paper sycamore models with different wing sizes take to fall.
Common mistake: pollination is not dispersal. Pollination moves pollen to a stigma; dispersal moves seeds away from the plant.
Mission 5 check
How does pollen get from flower to flower?
?A flower can't move from place to place. How does its pollen get to another flower's stigma?
Recap
The big ideas to remember
Cells & organisation: cells → tissues → organs → systems; plant cells have 3 extras (wall, vacuole, chloroplasts); materials diffuse in and out of cells, from high to low concentration.
Nutrition & digestion: balanced diet; enzymes are protein catalysts (not alive); food journey mouth → intestines; energy in a portion = energy per 100 g × mass ÷ 100.
Gas exchange: alveoli swap O₂ and CO₂; bell-jar model: bigger chest, lower pressure, air rushes in; lung volume measured by displacing water; breathing ≠ respiration; exercise: faster, deeper breathing; asthma narrows the airways; leaves swap gases through stomata.
Health: diet, exercise, drugs and smoking all affect body systems.
Reproduction: testes make sperm, ovaries release eggs; gametes join at fertilisation; menstrual cycle of about 28 days; gestation: the placenta passes food and oxygen, and harmful substances, to the foetus; plant pollination; seeds dispersed by wind, animals or bursting pods.
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