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GCSE Biology Revision

Inheritance, Variation & Evolution

DNA and inheritance, reproduction, variation, natural selection and evolution, and classification.

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What does it mean for an allele to be 'dominant'?

Inheritance, Variation & Evolution is a core part of GCSE Biology. Revise the key concepts and common mistakes below, then lock them in with the free games.

Key concepts

GeneShort section of DNA coding for a particular protein
AlleleDifferent version of the same gene (e.g. B or b)
GenotypeThe combination of alleles an organism carries
PhenotypeObservable characteristic produced by the genotype
HomozygousTwo identical alleles for a gene (BB or bb)
HeterozygousTwo different alleles for a gene (Bb)
Punnett squareGrid used to predict offspring genotypes from a cross
Monohybrid crossCross involving one gene with two alleles
Dominant alleleAllele expressed even when only one copy is present
Recessive alleleOnly expressed when both alleles are recessive
ProbabilityChance of an outcome — as fraction, ratio or %
CarrierHeterozygote carrying but not showing a recessive trait
SpeciationFormation of two new species from one ancestor
Selective breedingChoosing parents with desired traits to breed

What your exam board covers

Where Inheritance, Variation & Evolution sits in each exam board's specification. Tap a board to see what it lists.

AQAInheritance, variation and evolutionSpec 8461
  • Reproduction
  • Variation and evolution
  • The development of understanding of genetics and evolution
  • Classification of living organisms

Source: AQA GCSE Biology (8461) specification — Subject content, accessed 23 June 2026.

Eduqas/WJECInheritance, variation and evolutionSpec C400P
  • The genome and gene expression
  • Inheritance
  • Variation and evolution
  • Selective breeding and gene technology

Source: Eduqas GCSE Biology specification, accessed 9 July 2026.

Edexcel IGCSEReproduction and inheritanceSpec 4BI1
  • Reproduction
  • Inheritance

Source: Pearson Edexcel International GCSE Biology (4BI1) specification, accessed 23 June 2026.

Learn Inheritance, Variation & Evolution step by step

Free interactive mini-lessons: short screens, worked examples and quick checks. Pick your exam board:

Common mistakes to avoid

Questions where students often pick the tempting wrong answer — make sure you know the right one:

What does it mean for an allele to be 'dominant'?✗ A dominant allele is the most common allele in a population.   ✓ It is expressed in the phenotype when at least one copy is present (in a heterozygote).
What does a gene code for?✗ A gene codes for a specific physical feature like eye colour directly.   ✓ Typically a polypeptide (protein) — through transcription to mRNA and translation by ribosomes.
How does a population of organisms become better adapted to its environment over time?✗ Individual organisms change during their lifetime in response to their environment and pass the changes on to offspring.   ✓ Individuals with advantageous heritable variations survive and reproduce more; their alleles increase in frequency over generations.
Is a mutation always harmful to an organism?✗ Every mutation is harmful and damages the organism.   ✓ No — most mutations are neutral (no effect), some are harmful, and a few are beneficial.
Where in a cell is DNA mostly found?✗ In the cytoplasm   ✓ In the nucleus

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