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Cambridge IGCSE Biology (0610) · Coordination & response
Mini-Lesson

Coordination & response

This mini-lesson walks you through Cambridge IGCSE Coordination & response: the nervous system and the reflex arc, the eye, hormones & endocrine glands, homeostasis (blood glucose and temperature), and tropisms & auxin.

Make a guess: how can your hand move before you think?

  1. Mission 1How can you move before you think?
  2. Mission 2What keeps your blood glucose steady?

Work through each screen, answer the questions as you go (some wordy, some calculations) and collect ⭐ stars. Watch for the Key term flags. Press Start when you're ready.

Coordination · nervous system

The nervous system & reflex arc

The nervous system uses fast electrical impulses along neurones. It has the central nervous system (CNS) — the brain and spinal cord — and the peripheral nervous system (PNS), the nerves. A reflex is a fast, automatic response that protects the body (e.g. pulling your hand away from a hot object). Its pathway is the reflex arc:

receptor sensory neurone relay neurone (CNS) motor neurone effector (muscle) stimulus response synapses between neurones
Reflexes bypass conscious thought, so they are very fast — protecting you from harm.

Synapse: where two neurones meet there is a tiny gap called a synapse. The impulse crosses it using a chemical (neurotransmitter), which then triggers a new impulse in the next neurone.

Quick check

Put the arc in order

?Which shows the correct order of the reflex arc after a stimulus?
Mission 1 check

How can you move before you think?

?Walking barefoot, Sam treads on a sharp stone. His foot lifts before he even feels the pain. How can his foot move before he thinks?
Coordination · the eye

The eye

The eye is a sense organ that detects light. Learn these key parts and jobs:

iris lens pupil cornea retina optic nerve
Light path: cornea → pupil → lens → retina; the optic nerve carries impulses to the brain.
  • Cornea — transparent front; does most of the focusing (refraction).
  • Iris — controls the size of the pupil, so it controls how much light enters.
  • Lens — fine-focuses light onto the retina (changes shape for near/far — accommodation).
  • Retina — contains light receptors that make impulses.
  • Optic nerve — carries impulses to the brain.

Pupil reflex: in bright light the circular iris muscles contract (radial muscles relax) and the pupil gets smaller, protecting the retina. In dim light the radial muscles contract (circular relax) and the pupil gets larger. The two sets of muscles are antagonistic.

Coordination · hormones

Hormones & endocrine glands

A hormone is a chemical made by an endocrine gland, carried in the blood to target organs. Hormonal responses are usually slower but longer-lasting than nervous ones.

  • Adrenal glands → adrenaline — the "fight or flight" hormone (raises heart rate, breathing rate and blood glucose).
  • Pancreas → insulin and glucagon — control blood glucose.
  • Ovaries → oestrogen; testes → testosterone — control sexual development.
nervous: fast, short-lived electrical impulses along neurones · precise target hormonal: slower, longer-lasting chemicals carried in the blood · wider effect
Two control systems: electrical (nervous) and chemical (hormonal).
Sort it

Nervous or hormonal?

Tap a feature, then tap which control system it describes. (Some are true of both.)

🔁 Both

⚡ Nervous

🧪 Hormonal

Mission 2 of 2

What keeps your blood glucose steady?

Make a guess: what keeps your blood glucose steady?

Key term · homeostasis

Homeostasis — glucose & temperature

Homeostasis is keeping a constant internal environment. It works by negative feedback: if a level rises too high, the body brings it down, and vice versa.

Blood glucose is controlled by the pancreas:

  • Glucose too high → pancreas releases insulin → liver converts glucose to glycogen → glucose falls.
  • Glucose too low → pancreas releases glucagon → liver converts glycogen back to glucose → glucose rises.

Temperature (set point about 37 °C) is controlled by the brain, which sends signals to the skin:

  • Too hot → sweating (evaporation cools) and vasodilation (more blood near the skin loses heat).
  • Too cold → shivering (respiration releases heat) and vasoconstriction (less blood near the skin keeps heat in).

Watch out: in diabetes, the body cannot control blood glucose well — Type 1 is treated with insulin injections. Insulin lowers glucose; glucagon raises it.

Quick check

After a sugary meal

?Just after a sugary meal, blood glucose rises. Which hormone is released, and what does it make the liver do?
Mission 2 check

What keeps your blood glucose steady?

?Sam is healthy. After a large sugary drink, his blood glucose rises, then returns to normal within two hours. Which chain of events brought it back down?
Calculate

Your turn — temperature change

1Normal core body temperature is 37.0 °C. A patient's temperature is measured at 39.4 °C. Calculate how many degrees above normal this is.
°C
Hint: difference = 39.4 − 37.0.
Calculate

Your turn — mean reaction time

2In a ruler-drop reaction test, three readings are 0.18 s, 0.22 s and 0.20 s. Calculate the mean reaction time.
s
Hint: mean = (0.18 + 0.22 + 0.20) ÷ 3 = 0.60 ÷ 3.
Coordination · plant responses

Tropisms & auxin

Plants respond to stimuli by growing — this is a tropism. The response is controlled by a plant hormone called auxin.

  • Phototropism — growth in response to light. Shoots grow towards light (positive phototropism).
  • Gravitropism (geotropism) — growth in response to gravity. Roots grow downwards (positive gravitropism); shoots grow upwards.

How auxin works in a shoot: auxin gathers on the shaded side of the shoot. It makes those cells grow (elongate) more, so the shoot bends towards the light.

☀️ light shaded side: more auxin, so cells elongate more lit side: less auxin, grows less tip bends towards the light
Uneven auxin means uneven growth, which bends the shoot towards the light.
Quick check

Why does the shoot bend?

?A shoot is lit from one side and bends towards the light. What does auxin do to cause this?
Match it

Match each gland/hormone to its job

Tap a job on the left, then its matching hormone on the right.

Job
Hormone
Quick check

Nervous vs hormonal

?Which statement correctly compares nervous and hormonal control?
Recap

The big ideas to know

Nervous system: CNS (brain + spinal cord) + peripheral nerves; fast electrical impulses

Reflex arc: receptor → sensory → relay → motor → effector (synapses between)

Eye: cornea + lens focus light on the retina; iris controls the pupil (pupil reflex)

Hormones: chemicals from endocrine glands in the blood; slower, longer-lasting

Homeostasis: glucose (insulin lowers, glucagon raises); temperature (sweat/vasodilation vs shiver/vasoconstriction)

Tropisms: phototropism & gravitropism; auxin gathers on the shaded side → shoot bends to light

You've covered the key ideas in Cambridge IGCSE Coordination & response. Press Finish to see your score.

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