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CCEA GCSE Biology · Breathing & respiration
Mini-Lesson

Breathing & respiration

This mini-lesson covers the CCEA topic Breathing & the respiratory system: aerobic and anaerobic respiration (in muscle and yeast), the breathing system and how we ventilate the lungs, gas exchange at the alveoli, and simple breathing-rate calculations.

respiration energy released in cells breathing air moving in and out of lungs two different things — don't mix them up!

Work through each screen, answer the questions as you go (some are wordy, some are calculations) and collect ⭐ stars. Press Start when you're ready.

Respiration · what it is

Respiration is not breathing

Respiration is the chemical process that releases energy from glucose. It happens in all living cells, all the time — the aerobic form takes place mainly in the mitochondria.

Breathing (ventilation) is completely different: it is the movement of air in and out of the lungs. Breathing supplies the oxygen and removes the carbon dioxide that respiration uses and produces — but breathing itself releases no energy.

energy released movement (muscles) growth keeping warm (heat) active transport & reproduction
The energy released by respiration is used for movement, growth, keeping warm, active transport and reproduction.

Watch out: respiration releases energy — it does not "make" or "create" energy. And it happens in every living cell, not just in the lungs.

Respiration · aerobic

Aerobic respiration

Aerobic respiration uses oxygen to fully break down glucose. It releases a large amount of energy per glucose molecule.

glucose + oxygen → carbon dioxide + water(energy is released)  ·  symbol: C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O
  • Reactants: glucose and oxygen.
  • Products: carbon dioxide and water.
  • Site: mainly the mitochondria of the cell.
  • Energy: a lot — glucose is completely broken down.

Balanced symbol equation: C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O. Notice there are 6 carbons, 12 hydrogens and 18 oxygens on each side — it balances.

Quick check

What comes out?

?In aerobic respiration, glucose reacts with oxygen. What are the two products formed?
Respiration · anaerobic

Anaerobic respiration

Anaerobic respiration is respiration without oxygen. Glucose is only partly broken down, so it releases much less energy per glucose than aerobic respiration. CCEA needs both of these word equations:

glucose → lactic acidin mammalian muscle during hard exercise (a little energy released)
glucose → ethanol + carbon dioxidein yeast — called fermentation (a little energy released)
  • In muscle: during vigorous exercise, oxygen can't reach the muscles fast enough, so they respire anaerobically and make lactic acid.
  • The lactic acid builds up, causing an oxygen debt and muscle fatigue. Extra oxygen is needed afterwards to break it down.
  • In yeast: yeast respires anaerobically to make ethanol + carbon dioxide — used in brewing (alcohol) and baking (the CO₂ makes bread rise).

Key difference: anaerobic respiration releases far less energy per glucose than aerobic, because the glucose is not fully broken down.

Sort it

Which kind of respiration?

Tap a statement, then tap the box it belongs to.

🫁 Aerobic

💪 Anaerobic (muscle)

🍺 Anaerobic (yeast)

Quick check

The sprinter's problem

?A sprinter's leg muscles run out of oxygen during a hard race. What substance builds up when muscle respires anaerobically?
Quick check

Yeast & energy

?Which statement is correct about respiration?
Breathing · the respiratory system

The breathing system

Air travels from the nasal cavity down the trachea, which splits into two bronchi, then into smaller bronchioles, ending in tiny air sacs called alveoli — where gas exchange happens.

trachea bronchus bronchioles alveoli lung diaphragm
Air path: nasal cavity → trachea → bronchi → bronchioles → alveoli. The ribs, intercostal muscles and diaphragm move air in and out.

Also learn: the lungs sit inside the ribs and are protected by pleural membranes with a thin layer of pleural fluid between them, which reduces friction as the lungs move.

Breathing · ventilation

How we breathe in and out

Breathing works by changing the volume of the thorax, which changes the pressure inside. Air always moves from high pressure to low pressure.

Breathing IN (inhalation)

Intercostal muscles contract → ribs move up and out.

Diaphragm contracts and flattens (moves down).

Thorax volume increases → pressure inside decreases → air moves IN.

Breathing OUT (exhalation)

Intercostal muscles relax → ribs move down and in.

Diaphragm relaxes and domes up.

Thorax volume decreases → pressure inside increases → air is pushed OUT.

Remember the chain: muscles → volume → pressure → air movement. Breathing in and breathing out are the exact opposites of each other.

Quick check

What does the diaphragm do?

?When you breathe in, what happens to the diaphragm?
Breathing · gas exchange

Gas exchange at the alveoli

At the alveoli, gases move by diffusion down their concentration gradients:

  • Oxygen diffuses from the alveolus into the blood.
  • Carbon dioxide diffuses from the blood into the alveolus to be breathed out.

Exchange surfaces are adapted to make diffusion fast: a large surface area, thin walls (short diffusion distance), moist, permeable, a good blood supply, and a steep concentration gradient kept up by breathing.

Inhaled air Exhaled air Oxygen: ~21% CO₂: ~0.04% Nitrogen: ~78% Oxygen: ~16% CO₂: ~4% Nitrogen: ~78%
Exhaled air has less oxygen, more carbon dioxide and more water vapour than inhaled air. Nitrogen (~78%) is unchanged.
Quick check

Breathe out

?Compared with the air you breathe in, which gas is present in a higher amount in the air you breathe out?
Calculate

Your turn — breathing rate

1At rest, a student takes 30 breaths in 2 minutes. Calculate their breathing rate in breaths per minute.
breaths/min
Hint: breathing rate = breaths ÷ minutes = 30 ÷ 2.
Calculate

Your turn — oxygen used

2Inhaled air is about 21% oxygen; exhaled air is about 16% oxygen. Calculate the percentage of oxygen used by the body (the difference).
%
Hint: oxygen used = 21 − 16.
Match it

Inhalation or exhalation?

Tap an event on the left, then whether it happens during breathing in or breathing out.

Event
When?
Recap

The big ideas to know

Respiration ≠ breathing: respiration releases energy in all cells; breathing moves air in and out of the lungs

Aerobic: glucose + oxygen → carbon dioxide + water (lots of energy) · C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O

Anaerobic (muscle): glucose → lactic acid (oxygen debt) · (yeast): glucose → ethanol + CO₂ — much less energy

Breathing in: intercostals + diaphragm contract → thorax bigger → pressure lower → air in (out = the opposite)

Gas exchange: O₂ into blood, CO₂ out, by diffusion; exhaled air = less O₂, more CO₂ & water vapour

You've covered CCEA Breathing & respiration. Press Finish to see your score.

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