Innate defences are fast and non-specific: skin and mucous barriers, blood clotting, and phagocytes.
Adaptive immunity is specific: B-lymphocytes make antibodies, and memory cells give a faster, stronger secondary response. Vaccines exploit this, and high uptake gives herd immunity.
Calculate
Your turn — calculate
2A vaccine gives 95% protection. In a group of 400 vaccinated people who are all exposed, calculate the expected number not protected.
people
Hint: 5% are unprotected, so 0.05 × 400.
C3.2 Defence
Antibodies and epidemiology (HL)
Monoclonal antibodies are identical antibodies from one B-cell clone; because each binds a single antigen, they are used in diagnosis (e.g. pregnancy tests) and therapy.
Epidemiology tracks disease spread. Concerns include antibiotic resistance, HIV/AIDS (a retrovirus that destroys helper T-cells) and zoonoses that jump from animals to humans.
Sort it
Sort each item into its group
Sort each process into the correct control or defence system.
Nervous control
Hormonal control
Immune defence
Quick check
Question
?The region of the brain that coordinates fine movement and balance is the...
Quick check
Question
?The secondary immune response is faster and stronger than the primary response because of...
Quick check
Question
?Compared with nervous control, hormonal (endocrine) control is generally...
Match it
Match each item to its partner
Match each structure or term to its role.
Item
Partner
Quick check
Question
?Monoclonal antibodies are useful in diagnosis because they...
Recap
The big ideas to take away
C3.1 (HL): nervous vs hormonal control; cerebellum, medulla, hypothalamus/pituitary
C3.2: innate vs adaptive immunity; memory cells and the secondary response